Skip to main content

Table 2 Clinical characteristics of 500 patients with POI

From: Next-generation sequencing of 500 POI patients identified novel responsible monogenic and oligogenic variants

Characteristic

500 POI patients (mean ± SD)

Age (29)

29.72 ± 4.36

FSH* (IU/L)

69.10 ± 31.79

E2* (pg/ml)

21.33 ± 16.73

BMI (kg/m2)

21.37 ± 6.64

Age at menarche (29)

14.62 ± 3.04

Onset age of POI (29)

23.97 ± 5.71

Karyotype b

46, XX

PA/SA (%) a

22.7%/77.3%

  1. * Hormone levels are the basis levels tested during menstruation
  2. aPA Primary amenorrhea, SA Secondary amenorrhea
  3. b All the patients have been tested their karyotype