Combined use of CA125, neutrophil/lymphocyte ratio and platelet/lymphocyte ratio for the diagnosis of borderline and malignant epithelial ovarian tumors

Table 3 Cut-off value and diagnostic value of CA125, NLR and PLR in the diagnosis of EOTs

Variable	Groups	AUC	Cut-off	P-value	Sensitivity (%)	Specificity (%)	Comparison of AUC
Variable	Groups	AUC	Cut-off	P-value	Sensitivity (%)	Specificity (%)	Groups	P-value
Benign vs. malignant	CA125	0.9417	35	< 0.0001	70.31	100	a vs.b	0.5948
	NLR	0.9271	1.760	< 0.0001	79.69	90.97	b vs. c	0.5645
	PLR	0.9399	114.3	< 0.0001	84.38	92.9	a vs. c	0.9506
Benign vs. borderline	CA125	0.8069	18.72	< 0.0001	53.97	100	a vs. b	0.5600
	NLR	0.8345	1.244	< 0.0001	87.5	69.87	b vs. c	0.0359
	PLR	0.8993	89	< 0.0001	92.06	75.48	a vs. c	0.0142
Borderline vs. malignant	CA125	0.7557	42.74	< 0.0001	67.19	77.78	a vs. b	0.2115
	NLR	0.6942	2.687	0.0001	46.88	85.71	b vs. c	0.6678
	PLR	0.666	213.6	0.0006	34.85	93.75	a vs. c	0.1265

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