Skip to main content
Fig. 5 | Journal of Ovarian Research

Fig. 5

From: LncRNA DANCR counteracts premature ovarian insufficiency by regulating the senescence process of granulosa cells through stabilizing the interaction between p53 and hNRNPC

Fig. 5

DANCR binds to hNRNPC and p53, and regulates the interaction between hNRNPC and p53. RIP (A) and RNA pull down (B) assays was performed to detect the DANCR binding to hNRNPC and p53. C, The Co-IP results suggested that DANCR knockdown upregulated the p53 protein level and attenuated the interaction between hNRNPC and p53. The relative expression in histogram was calculated by Co-IP samples grayscale value / Input samples grayscale value. D, Co-localization fluorescence of hNRNPC and p53 indicated the effects of DANCR on the two proteins binding. Scale bar: 50 μm. *p < 0.05, ** p < 0.01, *** p < 0.001

Back to article page

Journal of Ovarian Research

ISSN: 1757-2215

Contact us