Fig. 2From: lncRNA-FMR6 directly binds SAV1 to increase apoptosis of granulosa cells in premature ovarian failureLncRNA-FMR6 silencing facilitated KGN cells proliferation and restrained apoptosis, while it upregulation resulted an opposite trend. A Relative levels of lncRNA-FMR6 in KGN cells transfected with either FMR6-pcDNA, empty vector, si-NC and si-FMR6, as assessed via RT-qPCR. **P < 0.01. B Effect of FMR6-pcDNA or si-FMR6 transfection on the proliferative ability of cells, as determined through CCK-8. **P < 0.01. C Effect of FMR6-pcDNA or si-FMR6 transfection on caspase-3, as determined by flow cytometry assay. **P < 0.01. D Effect of FMR6-pcDNA or si-FMR6 transfection on apoptosis rate, as determined by caspase-3 activity assay. **P < 0.01. E FMR6-pcDNA or si-FMR6 transfection’s effect on Bax and Bcl-2 mRNA levels, as ascertained via RT-qPCR. **P < 0.01Back to article page