Fig. 4

LncRNA-FMR6-dependent inhibitory effects of SAV1 on KGN cells apoptosis. A SAV1 mRNA levels in KGN cells delivered with si-NC, si-FMR6 or si-FMR6 + si-SAV1, as assessed via RT-qPCR. **P < 0.01. B SAV1 protein levels in KGN cells delivered with si-NC, si-FMR6 or si-FMR6 + si-SAV1, as assessed via western blotting. **P < 0.01. C Effect of si-NC, si-FMR6 or si-FMR6 + si-SAV1 transfection on the proliferative ability of cells, as determined by CCK-8 assay. **P < 0.01. D Effect of si-NC, si-FMR6 or si-FMR6 + si-SAV1 transfection on caspase-3 activity, as determined by caspase-3 activity assay. **P < 0.01. E Effect of si-NC, si-FMR6 or si-FMR6 + si-SAV1 transfection on apoptosis rate, as determined by flow cytometry assay. **P < 0.01. F si-NC, si-FMR6 or si-FMR6 + si-SAV1 transfection’s effect on Bax and Bcl-2 mRNA levels, as ascertained via RT-qPCR. **P < 0.01