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Fig. 1 | Journal of Ovarian Research

Fig. 1

From: Prognostic marker C3AR1 is associated with ovarian cancer cell proliferation and immunosuppression in the tumor microenvironment

Fig. 1

Analysis of the expression level of C3AR1 in pan-cancer. (A) The transcription level of C3AR1 in various cancer tissues in the GEPIA database. (B) C3AR1 mRNA expression levels in ovarian cancer and normal tissues in the GEPIA database. red (n = 426) tumor samples; gray (n = 88) normal samples. (C) C3AR1 protein levels in ovarian cancer and normal tissues in the CPTAC database. red (n = 84) tumor samples; blue (n = 19) normal samples. (D) The typical IHC staining of C3AR1 in ovarian cancer and normal tissues in the HPA database. (E, F) Correlation analysis between C3AR1 gene methylation levels (cg09238677, cg23205183) and transcription levels. Horizontal axis C3AR1 mRNA expression levels; vertical axis C3AR1 gene methylation levels. (G) OS analysis of C3AR1 in patients with ovarian cancer, (H) DFS and (I) PPS. DFS, disease-free survival; PPS, post progression survival; OS, overall survival. *P < 0.05; **P < 0.01; *** P < 0.001; ****P < 0.0001

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