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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: Prognostic marker C3AR1 is associated with ovarian cancer cell proliferation and immunosuppression in the tumor microenvironment

Fig. 4

Correlation between C3AR1 and OC tumor immune infiltration. (A) Correlation between C3AR1 expression and immune cell infiltration in OC in TIMER database. (B-D) C3AR1 expression is associated with M2 macrophages, tumor-associated macrophages and monocyte immune marker genes in ovarian cancer. Markers for M2 macrophages: CD163, MRC1, CD209, tumor-associated macrophages: CCL2, CD86, CD68, and monocytes: CD14, CD33, ITGAX. (E) Gene expression levels of 8 common immune checkpoint genes in the C3AR1 high and low expression group. ** p < 0.01,*** p < 0.001

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