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Fig. 1 | Journal of Ovarian Research

Fig. 1

From: Knockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM)

Fig. 1

The association of HSP60 with the prognosis of ovarian cancer patients and its expression in human ovarian cancer cell lines and tissues. A, B The curve plot for progression-free survival between HSPD1 high and low transcript groups in all OC and serous OC, respectively. The red line indicates patients with high HSPD1 levels and the black line indicates patients with low HSPD1 levels, log rank P = 0.01 and 0.00006, respectively. C Differential expression of HSP60 in the isolated mitochondria of OC cell lines. D Quantification analysis of the protein expression level in the C. E HSP60 expression was measured by IHC in tissue microarray. Representative images of strong (score 3), medium (score 2), weak (score 1), and negative (score 0) staining are shown. F IHC images of HSP60 in normal (upper) and OC (lower) tissues according to tissue microarray. G Statistical analysis of the protein expression of HSP60 according to the staining scores of OC and normal tissues. *P < 0.05, **P < 0.01

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