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Table 2 Odds ratios and adjusted odds ratios of pregnancy outcomes before and after binary logistic regression and IPW

From: Diminished ovarian reserve may not be associated with a poorer fresh cycle outcome in women < 38 years

 

Live birth

Crude Modela

Adjusted Model 1b

Adjusted Model 2c

 

n (%)

OR (95%CI)

P value

Adjusted OR (95%CI)

P(a) value1

Adjusted OR (95%CI)

P(a) value2

Fresh cyclesd

Groups

 DOR (n = 443)

178(40.2%)

0.672(0.553–0.816)

 < 0.001*

0.969 (0.785–1.195)

0.766

0.934 (0.750–1.164)

0.545

 Non-DOR (n = 7,736)

3866(50.0%)

Reference

 

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Reference

 

Blastocyst transferrede

 DOR (n = 18)

8 (44.4%)

0.697 (0.272–1.788)

0.453

1.454 (0.509–4.152)

0.485

0.504 (0.097–2.057)

0.359

 Non-DOR (n = 685)

366 (53.4%)

Reference

 

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Reference

 

Cleavage embryo transferrede

 DOR (n = 425)

170 (40.0%)

0.676 (0.553–0.825)

 < 0.001*

0.956 (0.772–1.185)

0.956

0.931 (0.745–1.162)

0.527

 Non-DOR (n = 7,051)

3502 (49.7%)

Reference

 

Reference

 

Reference

 

One embryo transferredf

 DOR with one embryo transferred (n = 281)

105 (37.4%)

0.694 (0.541–0.890)

0.004*

1.001 (0.765–1.310)

0.994

0.727 (0.550–0.956)

0.024*

 Non-DOR with one embryo transferred (n = 4348)

2010 (46.2%)

Reference

 

Reference

 

Reference

 

Two embryos transferredf

 DOR with two embryos transferred (n = 162)

73 (45.1%)

0.675 (0.492–0.927)

0.015*

0.907 (0.648–1.270)

0.571

1.228 (0.860–1.764)

0.220

 Non-DOR with two embryos transferred (n = 3388)

1856 (54.8%)

Reference

 

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Reference

 

Cumulative live birthg

 DOR (n = 443)

230 (51.9%)

0.414 (0.342–0.502)

 < 0.001*

0.604(0.491–0.744)

 < 0.001*

0.635 (0.510–0.794)

 < 0.001*

 Non-DOR (n = 7,736)

5589 (72.2%)

Reference

 

Reference

 

Reference

 
  1. aOdds ratios (ORs), 95% confidence intervals (CIs), and P values were based on the univariate analysis
  2. b Adjusted odds ratios (aORs), 95% confidence intervals (CIs), and P(a) values1 were based on the binary logistic regression
  3. c Adjusted odds ratios (aORs), 95% confidence intervals (CIs), and P(a) values2 were based on the inverse probability weighting
  4. d adjusted for female age, BMI, primary infertility, duration of infertility in years, infertility diagnosis, COS protocols, fertilization methods, number of embryos transferred, type of embryo transferred, and endometrial thickness
  5. e adjusted for female age, BMI, primary infertility, duration of infertility in years, infertility diagnosis, COS protocols, fertilization methods, number of embryos transferred, and endometrial thickness
  6. f adjusted for female age, BMI, primary infertility, duration of infertility in years, infertility diagnosis, COS protocols, fertilization methods, number of embryos transferred, type of embryo transferred, and endometrial thickness
  7. g adjusted for female age, BMI, primary infertility, duration of infertility in years, infertility diagnosis, COS protocols, and fertilization methods
  8. DOR diminished ovarian reserve
  9. *P < .05