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Table 3 Singleton abnormal perinatal outcome

From: Diminished ovarian reserve may not be associated with a poorer fresh cycle outcome in women < 38 years

 

Case (n = 183)

Control (n = 4320)

P value

P(a) value

Fresh cycles

141 (77.0%)

2949 (68.3%)

0.012*

-

FET cycles

42 (23.0%)

1371 (31.7%)

 

-

Age

31 (28–33)

30 (27–32)

 < 0.001*

-

BMI

21.9 (19.9–24.1)

21.3 (19.6–23.4)

0.034*

-

Male factor infertility

14 (7.7%)

1056 (24.4%)

 < 0.001*

-

Two embryos transferred

48 (26.2%)

1361 (31.5%)

0.132

-

Blastocyst

8 (4.4%)

485 (11.2%)

0.004*

-

HDP

9 (4.9%)

121 (2.8%)

0.094

0.202

Gestational diabetes mellitus

14 (7.7%)

250 (5.8%)

0.293

0.521

Abnormal placenta

4 (2.2%)

165 (3.8%)

0.255

0.277

Cesarean delivery

138 (75.4%)

3206 (74.2%)

0.717

0.684

Preterm delivery, < 37 wk

11 (6.0%)

261 (6.0%)

0.986

0.872

Very preterm delivery, < 32wk

1 (0.5%)

25 (0.6%)

0.955

0.869

Male gender

89 (48.6%)

2357 (54.6%)

0.115

0.096

Low birth weight, < 2,500 g

1 (0.5%)

49 (1.1%)

0.457

0.512

Macrosomia, > 4000 g

14 (7.7%)

204 (4.7%)

0.071

0.140

Fetal malformation

3 (1.6%)

47 (1.1%)

0.486

0.940

  1. Continuous data are reported as medians (first quartile, third quartile) and analyzed by Mann–Whitney U tests
  2. Categorical data are reported as n (%) and analyzed by χ2
  3. P(a) values are based on binary logistic regression, adjusted for female age, BMI, primary infertility, duration of infertility in years, infertility diagnosis, COS protocols, fertilization methods, number of embryos transferred, type of embryo transferred, and from either fresh or FET cycles
  4. HDP hypertensive disorders of pregnancy
  5. *P < .05