Fig. 3

Validation and estimation of the ovarian cancer (OV) prognostic signature based on the autophagy-related genes (ATGs). The distribution of risk-scores, survival status and survival time (months) of ovarian cancer (OV) individuals among the (A) TCGA-OV training set and (B) ICGC-OV validation set. The scatter plots showed risk-scores of OV patients, refer to corresponding survival status and survival (top and middle). The heatmaps (bottom) represented the expression profiles of the gene signature of FOXO1 and CASP8 in two risk groups. The Kaplan–Meier (K-M) overall survival curves for OV patients of the (C) TCGA-OV training set and (D) ICGC-OV validation set, which were classified into low-risk and high-risk groups. The ROC analysis for the OS prediction value of the autophagy-related signature, among both the (E) TCGA-OV training set and (F) ICGC-OV validation set