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Table 3 PD-L1 expression and tumor-associated lymphocytes in UTROSCT

From: PD-L1 expression, morphology, and molecular characteristic of a subset of aggressive uterine tumor resembling ovarian sex cord tumor and a literature review

 

UTROSCT (n)

Benign behavior (n = 10)

Malignant behavior (n = 4)

GREB1-rearranged (n = 2)

ESR1-rearranged (n = 4)

Tumoral PD-L1 (/mm2) (mean, range)

38.8(1-260)

34.0(0-120)

35.5(1–70)

6.0(0–12)

Stromal PD-L1 (/mm2) (mean, range)

2.7 (0–82)

28.0(0–82)

1.0 (0–2)

1.5(0–5)

PD-L1 (CPS)

(mean, range)

6.9 (0.11-52)

3.5 (0–10)

4.4 (0.11–8.75)

0.7(0-1.07)

CD8 + lymphocytes (/mm2) (mean, range)

105.4(20–350)

71.3(15–170)

102.5(30–175)

142.5(25–350)

FOXP3 + lymphocytes(/mm2) (mean, range)

3.4 (0–10)

42.0(0-150)

4.5 (1–8)

5.0 (3–7)