Figure 1

CCL25 inhibits cisplatin-induced cell death. OVCAR-3 and SKOV-3 cells were cultured with 0 (circles) or 100 ng/ml of CCL25 plus isotype control (squares) or anti-CCR9 (triangles) antibodies for 24 hours, along with increasing concentrations of cisplatin. Cell proliferation was determined by BrdU incorporation and assays were repeated 3 times and performed in triplicate. Asterisk(s) (*) indicate statistical significant differences (p < 0.01) between CCL25-treated and untreated OvCa cells.