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Figure 4 | Journal of Ovarian Research

Figure 4

From: Insulin and insulin-like growth factor signaling increases proliferation and hyperplasia of the ovarian surface epithelium and decreases follicular integrity through upregulation of the PI3-kinase pathway

Figure 4

IGF-I increases pGSK3β signaling in the OSE. Organoids were cultured 7d in basal media or media containing 5 μg/ml insulin or IGF-I, with or without the addition of 10 μM AG1024. Tissues were stained for expression of GSK3β phosphorylated at Ser9 (A) or total GSK3β protein (B). All images are 400X.

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Journal of Ovarian Research

ISSN: 1757-2215

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