Figure 7From: Insulin and insulin-like growth factor signaling increases proliferation and hyperplasia of the ovarian surface epithelium and decreases follicular integrity through upregulation of the PI3-kinase pathway High levels of insulin and IGF-I decrease secondary follicle MIS expression. Organoids were cultured for 7d in the indicated media. Tissues were stained for expression of MIS. All images are 100X.Back to article page