Table 2 Summary of the IC ₅₀ values (μM) and Resistance Factors (RF) for CS, CB, OX, CH1 and BORT as applied to the ovarian cancer cell lines A2780, A2780^cisR, A2780^ZD0473R and SKOV-3

CS

0.5 ± 0.03

8.2 ± 0.6

17.7

6.0 ± 0.5

13.0

10.2 ± 0.5

22.2

CB

14.0 ± 1.4

48.9 ± 3.9

3.5

64.6 ± 3.2

4.6

43.4 ± 3.9

3.1

OX

0.2 ± 0.01

0.4 ± 0.02

1.9

0.4 ± 0.03

2.1

43.6 ± 3.0

229.4

CH1

21.3 ± 2.0

26.6 ± 1.9

1.2

25.4 ± 1.7

1.2

29.8 ± 1.8

1.4

BORT

0.05 ± 0.01

0.05 ± 0.01

1.0

0.04 ± 0.01

0.8

0.09 ± 0.01

1.8