Cancer pathway | Gene | Description | Fold change |
---|---|---|---|
Cell adhesion | PNN | Pinin, desmosome-associated protein | 2.2 |
FAT1 | Cadherin-related tumor suppressor homolog | 2.3 | |
Cell cyclus | BRMS1 | Breast cancer metastase suppressor, transcriptional repressor | 2.0 |
NF2 | Neurofibromin | 2.2 | |
Cell cyclus and transcription factor | RB1 | Retinoblastoma, tumor suppressor, transcriptional repressor | 2.2 |
TP53 | Tumor suppressor, transcription factor | 2.3 | |
Cell cyclus or cell proliferation | NME1 | Expressed in Non-Metastatic cells, nucleoside diphosphate kinase | 3.2 |
Cell growth and proliferation | SSTR2 | Somatostatin receptor 2, ligand somatostatin 14/28 | 2,1 |
DENR | Density-regulated protein, involved in translation | 2.6 | |
KISS1R | Receptor for KISS1 | 2.8 | |
FLT4 | Receptor tyrosine kinase, ligand VEGF C/D | 3.1 | |
CXCR4 | CXC chemokine receptor, ligand SDF-1 | 3.4 | |
EPHB2 | Receptor tyrosine kinase, ligand ephrin-family members | 10.3 | |
Invasion | MMP10 | Matrix metalloproteinase | 2.4 |
MMP9 | Matrix metalloproteinase | 5.3 | |
Other | METAP2 | Methionyl aminopeptidase | 2.1 |
CD82 | Metastasis suppressor | 2.2 | |
CTSK | Cathepsin K, cysteine protease | 4.2 | |
NME4 | Expressed in Non-Metastatic cells, nucleoside diphosphate kinase | 7.6 | |
KISS1 | Metastasis suppressor | 14.6 | |
Transcription factor | MYCL1 | Myc-related | -3.8 |
SMAD4 | SMAD family member, | 2.0 | |
NR4A3 | Nuclear-receptor subfamily 4 member A3, potential transcriptional activator | 20.6 |