Table 1 Comparison between IVF cycles with hCG versus double trigger (GnRH-ag + hCG)
hCG | Double trigger | p values | |
|---|---|---|---|
Number of gonadotropin ampoules used | 38.5 ± 24.5 | 49.8 ± 15.4 | ns |
Length of stimulation (days) | 10.7 ± 2.5 | 10.7 ± 2.2 | ns |
Total number of gonadotropin used | 39 ± 25 | 49 ± 15 | ns |
Peak E2 levels on day of hCG administration (pmol/l) | 5402 ± 1983 | 4642 ± 2483 | ns |
Progesterone levels on day of hCG administration (nmol/l) | 1.7 ± 0.9 | 1,5 ± 0.7 | ns |
Number of follicles of >14 mm on day of hCG administration | 8.0 ± 3.5 | 6.4 ± 4.3 | ns |
Number of follicles of >10 mm on day of hCG administration | 10.6 ± 5.8 | 8.2 ± 4.3 | ns |
Number of oocytes retrieved | 2.3 ± 2.5 | 7.0 ± 4.6 | p < 0.02 |
Number of 2PN embryos | 1.7 ± 1.2 | 6.0 ± 4.6 | p < 0.002 |
Number of top quality embryos | 0.4 ± 0.5 | 3.7 ± 0.8 | p = 0.06 |
Number of embryos transferred | 0.85 ± 0.9 | 2.2 ± 0.7 | p < 0.002 |
Number of oocytes retrieved per number follicles of >14 mm on day of hCG administration (%) | 23.7 ± 21.5 | 118.0 ± 71.2 | p < 0.01 |
Number of oocytes retrieved per number follicles of >10 mm on day of hCG administration (%) | 18.5 ± 16.6 | 80.3 ± 31.1 | p < <0.001 |
Positive hCG (%) | 0 (0/8) | 62.5% (5/8) | p < 0.001 |
Clinical ongoing pregnancy (%) | 0 (0/8) | 37.5% (3/8) | p < 0.03 |