Fig. 5
From: MiRNA-149 modulates chemosensitivity of ovarian cancer A2780 cells to paclitaxel by targeting MyD88
Analysis of apoptosis in A2780 cells with miRNA-149 down-regulation. a Apoptosis in miRNA-149-down-regulated A2780 cells was analyzed by Annexin V-PE staining after treatment with paclitaxel. Data are presented as the mean ± SD of three independent experiments. b Apoptosis rates of miRNA-149-down-regulated and control cells. Asterisk refers to p < 0.01. c Real-time PCR analysis of Bax and Bcl-2 mRNA expression. The results were normalized to the amount of β-actin. Each value represents the average of 3 independent experiments. Asterisk refers to p < 0.01. d Western blot analysis of Bcl-2, Bax and MyD88 proteins expression in each group. β-actin expression served as the loading control