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Table 1 Baseline characteristics of infertile couples undergoing ICSI and selected for CLCG oocyte evaluation

From: Impact of oocytes with CLCG on ICSI outcomes and their potential relation to pesticide exposure

 

LCLCG

(n = 83)

HCLCG

(n = 68)

p-value

Female characteristics

Age (years)

30 ± 6.4

29 ± 6.4

ns

Tobacco use (%)

40%

31%

ns

FSH level at day 3 (IU/ML)

6.1 ± 1.5

6.5 ± 2.3

ns

E2 level at day 3 (pg/mL)

41.8 ± 12.3

42.9 ± 9.5

ns

AMH (ng/mL)

2.1 ± 0.4

2.2 ± 0.3

ns

Male characteristics

Age (years)

34 ± 7.8

33 ± 5.5

ns

Tobacco use (%)

36%

34%

ns

Sperm concentration (Ă—106/mL)

18 ± 16.5

22.5 ± 20.1

ns

Sperm motility (%)

26%

30%

ns

Normal morphologya (%)

23%

28%

ns

Infertility duration (years)

3.4 ± 1.9

3.6 ± 2.7

ns

Secondary infertility (%)

23%

20%

ns

Infertility type

Tubal factor

11%

18%

ns

Ovulatory factor

24%

16%

ns

Endometriosis

59%

59%

ns

Uterine factor

8%

6%

ns

ICSI attempt

2 ± 1.1

2 ± 1.2

ns

COS characteristics

GnRH antagonist use (%)

15%

22%

ns

COS duration (days)

11.6 ± 2.3

11.2 ± 1.9

ns

FSH total dose (IU)

1967 ± 935

2219 ± 1203

ns

E2 level at trigger day (pg/mL)

2760 ± 1142

2627 ± 1076

ns

Endometrial thickness at trigger day (mm)

10.7 ± 1.8

10.9 ± 2

ns

  1. Results are expressed as n(%) or mean (M) ± standard deviation (SD). A difference was considered significant (s) when P < 0.05; (ns): not significant
  2. LCLCG Low Centrally Located Cytoplasmic Granulation (CLCG) in a group of couples with oocytes exhibiting a low prevalence of CLCG of under 25%, HCLCG High CLCG in a group of couples with oocytes exhibiting a high prevalence of CLCG of over 75%, ICSI Intracytoplasmic Spermatozoa Injection, COS Controlled Ovarian Stimulation, FSH Follicle-Stimulating Hormone, AMH Anti-MĂ¼llerian Hormone, E2 Estradiol
  3. aSpermatozoa were evaluated by the Cohen-Bacrie modified morphology classification (normal forms ≥ 20%)