Characteristics | Singletons N = 361 | Twins N = 125 | Pa | |
---|---|---|---|---|
Maternal age, years | Â | 31.0 (28.0, 33.0) | 30.0 (28.0, 32.0) | 0.06 |
Preconception BMI, kg/m2 | Â | 23.9 (21.3, 27.0) | 24.0 (21.5, 27.3) | 0.59 |
AFC, n | Â | 16.0 (11.0, 21.0) | 16.0 (12.0, 22.0) | 0.24 |
Testosterone, nmol/L | Â | 0.7 (0.7, 1.1) | 0.7 (0.7, 1.0) | 0.90 |
AMH, ng/mL | Â | 4.9 (2.9, 7.4) | 5.2 (3.5, 8.2) | 0.07 |
Duration of infertility, years | Â | 3.0 (2.0, 4.0) | 3.0 (2.0, 5.0) | 0.81 |
T4, μg/dL |  | 7.9 (7.0, 9.0) | 8.2 (7.2, 9.2) | 0.11 |
FT4, ng/dL | Â | 1.3 (1.2, 1.4) | 1.3 (1.2, 1.4) | 0.18 |
TSH, μIU/mL |  | 2.1 (1.6, 2.9) | 2.1 (1.6, 3.0) | 0.74 |
TGAb, U/mL | Â | 15.6 (15.0, 24.6) | 16.0 (15.0, 27.5) | 0.54 |
TPOAb, U/mL | Â | 30.0 (28.0, 40.7) | 29.4 (28.0, 43.5) | 0.98 |
Positive TGAbb | No | 308 (85.3) | 105 (84.0) | 0.72 |
 | Yes | 53 (14.7) | 20 (16.0) |  |
Positive TPOAbb | No | 319 (88.4) | 110 (88.0) | 0.91 |
 | Yes | 42 (11.6) | 15 (12.0) |  |
Infertility type | Primary | 263 (72.9) | 102 (81.6) | 0.05 |
 | Secondary | 98 (27.1) | 23 (18.4) |  |
Ovarian stimulation regimen | GnRH antagonist | 274 (75.9) | 90 (72.0) | 0.55 |
 | Long GnRHa | 80 (22.2) | 31 (24.8) |  |
 | Othersbc | 7 (1.9) | 4 (3.2) |  |
Insemination technique | IVF | 265 (73.4) | 86 (68.8) | 0.35 |
 | ICSI | 96 (26.6) | 39 (31.2) |  |
Timing of embryo transfer | Day 3 | 344 (95.3) | 124 (99.2) | 0.16 |
 | Day 5 | 12 (3.3) | 1 (0.8) |  |
 | Day 6 | 5 (1.4) | 0 (0.0) |  |
Transferred embryos number, n | 1 | 49 (13.6) | 1 (0.8) |  < 0.001 |
 | 2 | 312 (86.4) | 124 (99.2) |  |
Gestational age, weeks |  < 37 | 330 (91.4) | 63 (50.4) |  < 0.001 |
 | 37 − 42 | 31 (8.6) | 62 (49.6) |  |
Delivery mode | Vaginal delivery | 165 (45.7) | 13 (10.4) |  < 0.001 |
 | Caesarean | 196 (54.3) | 112 (89.6) |  |
Neonatal sex | Male | 177 (49.0) | 128 (51.2) | 0.62 |
 | Female | 184 (51.0) | 122 (48.8) |  |
Birth weight, g |  < 2500 | 17 (4.7) | 130 (52.0) |  < 0.001 |
 | 2500 − 4000 | 320 (88.6) | 120 (48.0) |  |
 |  ≥ 4000 | 24 (6.6) | 0 (0.0) |  |