Fig. 6From: Dingkun pill alleviates metabolic abnormalities in polycystic ovary syndrome through brown adipose tissue activationDK treatment in PCOS mice activate the brown adipose metabolism and thermogenesis. (A) Heat map shows the expression level of differentially upregulated genes in OIL, DHEA and DHEA + DK groups. (B, C) B and C represent GO and KEGG analysis of the differentially expressed genes in DHEA and DHEA + DK groups, respectively. P values were determined by two-tailed Wilcoxon rank-sum test. (D, E, F) QRT-PCR analyzes the mRNA expression of lipid metabolism related Acox1, Mgll, Pnpla2 among OIL, OIL + DK, DHEA and DHEA + DK groups. (G, H) Lipid droplet content among OIL, OIL + DK, DHEA and DHEA + DK groups. All data were analyzed by one-way ANOVA with Tukey’s post hoc test. *P < 0.05, **P < 0.01, n = 3 per groupBack to article page