Fig. 1
From: DNA double-strand break genetic variants in patients with premature ovarian insufficiency
(By Figdraw(www.figdraw.com)): AÂ The main processes of programmed DSB formation and homologous recombination (HR) repair. The genes involved in each step are shown in the boxes and genes associated with POI pathogenesis are marked in red. BÂ The main processes and genes involved in non-homologous end joining repair (NHEJ). CÂ Schematic diagram of the structure and protein composition of the synaptonemal complex. DÂ Schematic diagram of the structure and protein composition of the cohesin complex in meiosis