Fig. 4

Omega-3 PUFAs modulate the gut microbiota of PCOS mice. A Bacterial taxonomic profiling at the genus level of intestinal bacteria from different mouse groups. B-K Relative abundance of Lachnospiraceae_NK4A136_group, Oscillibacter, Alistipes, Eubacterium_xylanophilum_group, Alloprevotella, Intestinimonas, Akkermansia, Blautia, Lachnospiraceae_UCG-006, and Roseburia. L Heatmap of the 21 OTUs in the control group altered in PCOS in response to omega-3 PUFA treatment. The phylum, family, and genus names of the OTUs are shown in the right panel. The color of the spots in the left panel represents the relative abundance at the genus level in each group. The analyses were conducted using R software version 3.3.1