Fig. 6

Omega-3 PUFAs improve the function and morphology of adipose tissues of PCOS in a gut microbiota–dependent manner. A Representative images of subcutaneous adipose tissues from control, PCOS, omega-3, and omega-3 + ABX mice. Scale bars: 50 μm. B-E Thermogenic markers in subcutaneous adipose tissues. F-I Thermogenic markers in brown adipose tissues. Error bars are expressed as the means ± SEMs. Statistical significance was determined by P values determined by one-way ANOVA followed by Dunnett’s multiple comparisons test (*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001)