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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: Mutations in CCNB3 affect its location thus causing a multiplicity of phenotypes in human oocytes maturation by aberrant CDK1 activity and APC/C activity at different stages

Fig. 4

CCNB3 mutations affect the location of CDK1 and the degradation of securin. (A) Immunofluorescence staining of CDK1 of oocyte injected with cRNA. Each group using 40 oocytes. (B) Fluorescence intensities (mean ± SEM) were quantified. (C) Immunofluorescence measurement of securin expressed of oocyte injected with cRNA and cultured for different times. Each treatment of one time using 6 oocytes. The scale bar represents 20 μm. (D) Fluorescence intensities (mean ± SEM) were quantified from the indicated number of oocytes imaged

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