Mutations in CCNB3 affect its location thus causing a multiplicity of phenotypes in human oocytes maturation by aberrant CDK1 activity and APC/C activity at different stages

Table 3 Oocyte and embryo characteristics of IVF and ICSI attempts for the affected individual

Patient	Cycle
Patient	IVF/ICSI Cycles	Total Number of Oocytes Retrieved	GV Oocytes	MI Oocytes	MII Oocytes	Fertilized Oocytes	No. of unknown oocyte stage	Cleaved Embryos	OMF type
Patient1	1(IVF)	14	0	1	5	0	8	0	IV
	2(ICSI)	12	4	1	4	0	1	2
	3(ICSI)	15	2	1	7	0	0	5
Patient2	1(IVF)	6	1	4	1	0	0	0	IV
Patient3	1(IVF)	14	0	14	0	0	0	0	II
Patient4	1(IVF)	5	0	4	0	1	0	0	IV
Patient5	1(ICSI)	8	0	3	0	5	0	0	IV
	2(ICSI)	13	0	12	0	1	0	0	IV

IVF-in vitro fertilization; ICSI-intracytoplasmic sperm injection; PB1-first polar body; OMF type-oocyte maturation failure type.
No. of unknown oocyte stage- some of the oocytes had multiple fragments and we cannot identify their specific periods

ISSN: 1757-2215