From: Genomic analyses of germline and somatic variation in high-grade serous ovarian cancer
 |  | COH 61 samples | TCGA 356 samples | ||||
---|---|---|---|---|---|---|---|
Gene | Region | Frequencya | HR (95%CI) | P | Frequencya | HR (95%CI) | P |
NOTCH3 | 19p13.12 | 13.11% | 2.26 (1.01—5.03) | 0.047 | 12.10% | 1.67 (1.14—2.39) | 0.01 |
ZNF536 | 19q12 | 9.84% | 3.14 (1.26—7.86) | 0.014 | 15.70% | 1.44 (1.02 -2.00) | 0.041 |
PIK3R2 | 19p13.11 | 8.19% | 2.95 (1.13—7.73) | 0.028 | 5.10% | 1.84 (1.01 -3.14) | 0.046 |