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Table 2 Association between genes with high-amplitude SCNAs and relapse-free survival

From: Genomic analyses of germline and somatic variation in high-grade serous ovarian cancer

  

COH 61 samples

TCGA 356 samples

Gene

Region

Frequencya

HR (95%CI)

P

Frequencya

HR (95%CI)

P

NOTCH3

19p13.12

13.11%

2.26 (1.01—5.03)

0.047

12.10%

1.67 (1.14—2.39)

0.01

ZNF536

19q12

9.84%

3.14 (1.26—7.86)

0.014

15.70%

1.44 (1.02 -2.00)

0.041

PIK3R2

19p13.11

8.19%

2.95 (1.13—7.73)

0.028

5.10%

1.84 (1.01 -3.14)

0.046

  1. aFrequency Percentage of samples carrying high amplitude SCNAs, HR Hazard ratio, CI Confidence interval