Fig. 4
From: Multi-omics reveal the metabolic patterns in mouse cumulus cells during oocyte maturation
Increased PGE2 generation in cumulus cells during oocyte maturation. A-C Relative levels of metabolites related to PGE2 synthesis in cumulus cells. D Schematic diagram of PGE2 synthesis in cumulus cells during maturation. Increased metabolites in cumulus cells during meiotic resumption are indicated by bold red arrows. Differential metabolic enzymes changes are indicated by blue triangles. E-N Relative abundance of the representative enzymes involved in PGE2 synthesis. Error bars, SD. Student’s t test was used for statistical analysis in all panels, comparing to GV cumulus cells. n.s., not significant