Table 3 Illustration of pooled and sub-group analysis under different genetic models

rs6165

OR (CI), p-value

 Dominant Model

1.04(0.93–1.16), 0.49

1.19 (0.92–1.16), 0.54

4%

1.04(0.92–1.18),

0.53

1.09(0.77–1.54),

0.63

0.6(0.25–1.47),

0.26

 Recessive Model

1.19(1.03–1.3),

0.02

1.2 (1.01–1.4),

0.04

10%

1.22(1.02–1.46),

0.03

1.27(0.93–1.73),

0.13

0.64(0.3–1.33),

0.23

 Additive Model

1.2(1.02–1.42),

0.03

1.19(0.96–1.47), 0.11

27%

1.23(1.02–1.49),

0.03

1.25(0.84–1.85),

0.16

0.48(0.18–1.34),

0.16

 Allele Model

1.07(0.99–1.18), 0.08

1.07(0.97–1.17), 0.19

25%

1.07(0.97–1.19),

0.18

1.15(0.93–1.41),

0.19

0.7(0.43–1.14),

0.16

rs6166

 Dominant Model

1.05(0.95–1.15),

0.34

1.04 (0.91–1.2)

0.56

44%

1.07 (0.95–1.2),

0.28

0.84 (0.66–1.06),

0.15

1.15 (0.95–1.39),

0.16

 Recessive Model

1.02(0.91–1.15),

0.72

0.97 (0.78–1.22),

0.82

61%

1.11 (0.92–1.32),

0.27

0.7 (0.54–0.9),

0.006*

1.02 (0.91–1.15),

0.11

 Additive Model

1.03 (0.90–1.2),

0.67

0.99 (0.76–1.29),

0.94

64%

1.1 (0.91–1.34),

0.33

0.65 (0.48–0.89),

0.006*

1.25 (0.98–1.59),

0.07

 Allele Model

1.03(0.96–1.10),

0.4

1.02 (0.90–1.15),

0.78

64%

1.06 (0.95–1.15),

0.19

0.82 (0.7–0.95),

0.01*

1.17 (1.04–1.32),

0.01*