Fig. 1From: Fance deficiency inhibits primordial germ cell proliferation associated with transcription–replication conflicts accumulate and DNA repair defectsReduced number of PGCs in Fance deficient mice during rapid mitosis. (A) Expression of the PGCs label protein SSEA1 was localized to the cell membrane in Fance+/+ and Fance−/− female embryonic mice at E11.5-E12.5. (B) The PGCs number of Fance−/− mice was significantly decreased than that of Fance+/+ mice. n = 4 embryos. All bars = 200 μmBack to article page