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Fig. 1 | Journal of Ovarian Research

Fig. 1

From: Fance deficiency inhibits primordial germ cell proliferation associated with transcription–replication conflicts accumulate and DNA repair defects

Fig. 1

Reduced number of PGCs in Fance deficient mice during rapid mitosis. (A) Expression of the PGCs label protein SSEA1 was localized to the cell membrane in Fance+/+ and Fance−/− female embryonic mice at E11.5-E12.5. (B) The PGCs number of Fance−/− mice was significantly decreased than that of Fance+/+ mice. n = 4 embryos. All bars = 200 μm

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