Fig. 5

Expression of DNA replication proteins in Fance^−/− PGCs and Fance^+/+ PGCs were not significantly different during rapid mitosis. (A) Representative images of co-localized staining of LIG1 and SSEA1 in Fance^−/− PGCs and Fance^+/+ PGCs. (B) There was no significant difference in the proportion of LIG1 positive PGCs between Fance^−/− and Fance^+/+ mice at E11.5 and E12.5. (C) Representative images of co-localized staining of PCNA and SSEA1 in Fance^−/− PGCs and Fance^+/+ PGCs. (D) There was no significant difference in the proportion of PCNA positive PGCs between Fance^−/− and Fance^+/+ mice at E11.5 and E12.5. n = 4 embryos. All bars = 200 μm