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Fig. 6 | Journal of Ovarian Research

Fig. 6

From: Fance deficiency inhibits primordial germ cell proliferation associated with transcription–replication conflicts accumulate and DNA repair defects

Fig. 6

TRCs accumulate in Fance deficient PGCs during rapid mitosis. (A) Representative images of co-localized staining of R-loop (recognized by the S9.6 antibody) and SSEA1 in Fance−/− PGCs and Fance+/+ PGCs. (B) The proportion of R-loop positive cells was significantly increased in Fance−/− PGCs compared to Fance+/+ PGCs. n = 4 embryos. All bars = 200 μm

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Journal of Ovarian Research

ISSN: 1757-2215

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