Fig. 7From: Fance deficiency inhibits primordial germ cell proliferation associated with transcription–replication conflicts accumulate and DNA repair defectsFance deficient PGCs down-regulated the FA pathway during rapid mitosis. (A) Representative images of co-localized staining of FANCD2 and SSEA1 in Fance−/− PGCs and Fance+/+ PGCs. (B) The proportion of FANCD2 positive cells was significantly decreased in Fance−/− PGCs compared to Fance+/+ PGCs. n = 4 embryos. All bars = 200 μmBack to article page