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Table 1 Association of PAPSS1 expression with clinicopathological factors in ovarian carcinoma patients

From: The PAPSS1 gene is a modulator of response to cisplatin by regulating estrogen receptor alpha signaling activity in ovarian cancer cells

Features

n

PAPSS1

χ2

P

Positive

Negative

 

Mean age

 > 50

79

49

30

0.715

0.398

Ascites

 ≤ 50

52

36

16

  

Positive

72

43

29

1.871

0.171

Negative

59

37

22

  

FIGO stage

I-II

68

35

33

11.168

0.001

III-IV

63

50

13

 

CA125 (U/ml)

 ≥ 200

79

48

31

1.487

0.223

 < 200

52

37

15

 

Pathological Subtype

Serous

92

71

21

20.481

0.000

Non serous

39

15

25

 

Tumor grade

G1

23

11

12

7.236

0.053

G2

70

43

27

 

G3

38

22

16

 

Tumor

 < 10

89

58

31

0.010

0.921

Size

 ≥ 10

42

27

15

  

Recurrent

Yes

82

59

23

4.804

0.028

(3 Years)

No

49

26

23

  

Metastasis

Yes

84

57

27

6.364

0.041

No

47

23

24

  

CRS

Yes

84

55

29

0.036

0.850

No

47

30

17

  

Platinum resistance

Present

35

27

8

4.395

0.040

Absent

96

50

46

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