Fig. 4

Knockdown of OIP5 inhibits proliferation and colony formation in ovarian cancer cells. A CCK8 assay was used to measure the change in the OD450 value from Day 1 to Day 5. B The OD450/fold is a multiple of the OD450 value of Day 1 to Day 5 relative to Day 1. The CCK8 assay showed that knockdown of OIP5 significantly inhibited the proliferation of ovarian cancer cells. CCK8, Cell counting kit-8. C EdU was used to measure the OD450 value on Day 1 and Day 4. D The OD450/fold is the multiple of the OD450 value of Day 4 relative to Day 1. EdU proliferation assays showed that OIP5 knockout significantly inhibited the proliferation of ovarian cancer cells. EdU, 5-Ethynyl-2-deoxyuridine. E and F Clone formation assays showed that knockdown of OIP5 suppressed colony formation ability. **P < 0.01, ***P < 0.001