Fig. 6
From: The role of OIP5 in the carcinogenesis and progression of ovarian cancer
Knockdown of OIP5 induces cell cycle arrest and apoptosis in ovarian can-cer cells. A and B Cell cycle distribution showed that OIP5 knockdown caused an increase in the number of cells in the G1 phase and a decrease in the number of cells in the S phase and G2/M phase among ovarian cancer cells. This indicated that the downregulation of OIP5 stalled cell cycle progression in the G1 phase. OIP5, Opa interacting protein 5. C OIP5 knockdown induced apoptosis in ovarian cancer cells. RFU, relative fluorescence units. **P < 0.01