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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: Identification of transcriptome characteristics of granulosa cells and the possible role of UBE2C in the pathogenesis of premature ovarian insufficiency

Fig. 2

Analysis of DEGs profile in GCs of patients with bPOI and controls. A Volcano plot of DEGs. The red dots represent the upregulated genes and the green dots represent the downregulated genes in bPOI group (|log2 (FC) |> 1; p value < 0.05). B Heatmap of DEGs, red indicates upregulated genes and blue indicates downregulated genes in the bPOI group. C GO enrichment analysis of DEGs. The top 10 BP, CC and MF terms of DEGs. D The top 25 KEGG pathway enrichment analysis of DEGs. (p value < 0.05). bPOI: biochemical premature ovarian insufficiency; CON: control; FC: fold change; GCs: granulosa cells; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; BP: biological process; MF: molecular function; CC: cellular component; DL represents the bPOI patient and NL represents the control patients

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Journal of Ovarian Research

ISSN: 1757-2215

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