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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Characterization of tumour microenvironment reprogramming reveals invasion in epithelial ovarian carcinoma

Fig. 5

Knockdown of EGR1 inhibits ovarian cancer cell migration and invasion. A A positive correlation was also observed between EMT activity and EGR1 expression in the GSE118828 dataset. B Knockout efficiency of EGR1 in SKOV3 and A2780 cell lines. C Evaluation of the effect of EGR1 on the migration and invasion of ovarian cancer cells by Transwell analysis. D Evaluation of the effect of EGR1 on the migration and invasion of ovarian cancer cells by wound healing analysis. E Significantly increased expression of E-cadherin and decreased expression of N-cadherin and Slug were observed after EGR1 silencing

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Journal of Ovarian Research

ISSN: 1757-2215

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