Table 1 Clinical characteristics and genotype frequencies of LHCGR rs2293275 variations in 205 patients triggered with r-hCG 250 μg

Female age (years)

30.15 (3.38)

30.01 (3.36)

30.65 (3.21)

0.496

Female BMI (kg/m²)

22.95 (2.99)

22.54 (3.02)

21.41 (2.63)

0.006

Basal hormone concentrations

 FSH (IU/L)

7.00 (1.87)

7.60 (1.85)

7.32 (2.03)

0.190

 LH (IU/L)

4.49 (2.96)

5.32 (3.25)

5.60 (4.14)

0.151

 AMH (ng/ml)

4.47 (2.63)

4.08 (1.78)

3.88 (2.01)

0.271

 AFC (n)

20.77 (10.75)

18.78 (8.53)

18.78 (8.47)

0.351

 Days of gonadotrophin (d)

10.30 (1.82)

10.15 (1.42)

9.56 (1.61)

0.020

 Total dose of gonadotrophin (IU)

2081.79 (852.96)

1743.28 (638.97)

1611.58 (441.49)

 < 0.001

 Days of antagonist (d)

4.97 (1.39)

4.75 (1.16)

4.63 (1.15)

0.264

Hormone concentrations on the trigger day

 LH (IU/L)

3.17 (2.33)

2.67 (1.98)

2.96 (2.04)

0.380

 E2 (pg/ml)

2576.07 (1324.02)

2789.03 (1693.88)

2373.03 (1162.01)

0.232

 P (ng/ml)

0.95 (0.41)

0.98 (0.50)

0.97 (0.62)

0.934

 No. of follicles (> = 12 mm) (n)

13.44 (5.07)

12.57 (4.91)

12.57 (4.35)

0.466

 No. of oocytes retrieved (n)

12.16 (5.85)

12.48 (5.87)

13.43 (4.55)

0.369

 Mature oocyte rate (× 100%)

0.84 (0.21)

0.84 (0.17)

0.87 (0.12)

0.563

 Follicle output rate (× 100%)

0.78 (0.40)

0.77 (0.36)

0.78 (0.37)

0.966

 Oocyte retrieval rate (× 100%)

0.91 (0.25)

0.99 (0.23)

1.08 (0.19)

 < 0.001

 Mature oocyte retrieval rate (× 100%)

0.76 (0.29)

0.84 (0.23)

0.93 (0.18)

 < 0.001

 Fertilization rate (× 100%)

0.68 (0.21)

0.70 (0.19)

0.75 (0.16)

0.088

 No. of high-quality embryos (n)

3.23 (2.50)

3.78 (2.46)

3.88 (2.48)

0.252

 No. of available embryos (n)

6.37 (4.88)

6.34 (3.70)

7.62 (3.38)

0.113

 Clinical pregnancy of fresh transfer (n)

19/36

23/40

11/27

0.396^a

LHCGR rs2293275 genotype

 GG

59

59

62

0.602^a

 AG

10

8

6

 AA

1

0

0