Table 2 Clinical characteristics and genotype frequencies of LHCGR rs2293275 variations in 167 patients triggered with triptorelin 0.2 mg

Female age (years)

29.79 (2.97)

28.85 (3.36)

29.45 (3.21)

0.290

Female BMI (kg/m²)

23.14 (3.34)

22.75 (2.91)

20.40 (2.22)

 < 0.001

Basal hormone concentrations

 FSH (IU/L)

6.76 (1.75)

7.45 (1.76)

7.44 (1.88)

0.072

 LH (IU/L)

5.42 (3.12)

5.44 (2.53)

7.01 (4.66)

0.028

 AMH (ng/ml)

7.68 (3.84)

8.01 (3.74)

8.17 (4.08)

0.798

 AFC (n)

29.11 (10.70)

30.32 (12.34)

29.38 (7.91)

0.814

 Days of gonadotrophin (d)

10.41 (1.82)

10.11 (1.41)

9.49 (1.25)

0.006

 Total dose of gonadotrophin (IU)

1794.42 (608.95)

1578.35 (474.48)

1222.50 (272.03)

 < 0.001

 Days of antagonist (d)

5.38 (1.60)

5.16 (1.22)

5.07 (0.94)

0.444

Hormone concentrations on the trigger day

 LH (IU/L)

2.89 (2.29)

3.27 (2.09)

3.22 (2.29)

0.624

 E2 (pg/ml)

5604.81 (2687.45)

6049.21 (2546.02)

5941.08 (2362.00)

0.628

 P (ng/ml)

1.32 (0.58)

1.51 (0.79)

1.24 (0.47)

0.073

 No. of follicles (> = 12 mm) (n)

24.64 (9.05)

25.20 (8.18)

24.75 (8.67)

0.937

 No. of oocytes retrieved (n)

19.59 (9.67)

23.88 (9.13)

26.62 (11.90)

0.002

 Mature oocyte rate (× 100%)

0.86 (0.15)

0.82 (0.14)

0.82 (0.13)

0.222

 Follicle output rate (× 100%)

0.94 (0.47)

0.94 (0.40)

0.87 (0.28)

0.580

 Oocyte retrieval rate (× 100%)

0.80 (0.29)

0.95 (0.21)

1.07 (0.19)

 < 0.001

 Mature oocyte retrieval rate (× 100%)

0.68 (0.27)

0.77 (0.21)

0.87 (0.21)

 < 0.001

 Fertilization rate (× 100%)

0.69 (0.23)

0.77 (0.15)

0.70 (0.18)

0.071

 No. of high-quality embryos (n)

5.39 (3.62)

7.11 (4.56)

7.38 (5.52)

0.051

  No. of available embryos (n)

10.32 (5.86)

13.68 (6.84)

14.13 (7.18)

0.005

 Clinical pregnancy of fresh transfer (n)

1/1

0/0

1/1

–-

LHCGR rs2293275 genotype

 GG

40

48

52

0.003^a

 AG

16

8

3

 AA

0

0

0