Table 3 Ovarian stimulation outcomes based on the genotypes of the LHCGR gene in patients triggered with r-hCG and GnRH-a
|  | r-hCG trigger (n = 204) | P value | GnRH-a trigger (n = 167) | P value | ||
|---|---|---|---|---|---|---|
Stimulation parameters and outcomes | GG genotype (n = 180) | AG Genotype (n = 24) |  | GG genotype (n = 140) | AG genotype (n = 27) |  |
BMI | 22.28 (2.89) | 22.24 (3.25) | 0.943 | 22.06 (3.09) | 22.36 (3.21) | 0.639 |
Days of gonadotrophin (d) | 10.01 (1.69) | 10.00 (1.38) | 0.975 | 9.92 (1.48) | 10.44 (1.83) | 0.109 |
Total dose of gonadotrophin (IU) | 1825.76 (709.98) | 1727.08 (584.92) | 0.515 | 1503.03 (497.47) | 1692.13 (644.78) | 0.088 |
Post-trigger hCG (LH) concentration (IU/L) | 93.72 (30.83) | 90.00 (39.95) | 0.593 | 60.91 (28.37) | 46.10 (15.70) |  < 0.001 |
ORR (× 100%) | 0.99 (0.24) | 0.98 (0.15) | 0.674 | 0.96 (0.26) | 0.85 (0.26) | 0.042 |
MORR (× 100%) | 0.84 (0.25) | 0.82 (0.23) | 0.683 | 0.79 (0.25) | 0.69 (0.19) | 0.042 |
Fertilization rate (× 100%) | 0.71 (0.19) | 0.73 (0.20) | 0.521 | 0.72 (0.19) | 0.71 (0.19) | 0.775 |
No.of high-quality embryos (n) | 3.55 (2.50) | 4.21 (2.41) | 0.224 | 6.89 (4.82) | 5.26 (3.69) | 0.053 |