Table 2 Cycle parameters and reproductive outcomes of repeated cycles between mLP and non-mLP groups
Group | MLP group | Non-mLP group | P |
|---|---|---|---|
Number | 50 | 50 | |
Cycle parameters | |||
Total Gn dose (IU) | 2443.00 ± 97.09 | 2521.00 ± 157.83 | 0.548 |
Days of Gn stimulation (days) | 8.30 ± 0.32 | 10.26 ± 0.44 | < 0.01 |
Features of trigger day | |||
FSH (IU/L) | 33.16(24.84–39.92) | 23.69(10.04–30.66) | < 0.01 |
LH (IU/L) | 3.92(2.34–5.48) | 2.46(1.45–6.38) | 0.039 |
E2 (ng/L) | 436.50(278.25–819.50) | 1179.00(595.50-1750.75) | < 0.01 |
Number of follicles ≥ 18 mm | 1.80 ± 0.17 | 1.50 ± 0.17 | 0.133 |
Endometrial thickness (mm) | 9.73 ± 0.36 | 10.35 ± 0.40 | 0.034 |
IVF laboratory parameters | |||
Number of oocytes retrieved | 4.16 ± 0.38 | 4.88 ± 0.70 | 0.860 |
Number of MII oocytes | 3.42 ± 2.47 | 3.56 ± 2.34 | 0.724 |
MII oocytes retrieved rate (%) | 82.21(171/208) | 82.03(178/217) | 0.961 |
Number of fertilized oocytes | 2.70 ± 2.24 | 3.30 ± 2.27 | 0.092 |
Fertilization rate (%) | 64.90(135/208) | 76.04(165/217) | 0.012 |
Normal fertilization rate (%) | 70.37(95/135) | 84.85(140/165) | < 0.01 |
Number of cleaved embryos | 3.04 ± 2.48 | 3.22 ± 2.17 | 0.617 |
Available embryos rate (%) | 62.91(95/151) | 50.35(72/143) | 0.03 |
Top-quality embryo rate (%) | 47.38(45/95) | 38.89(28/72) | 0.075 |
Pregnancy outcomes | |||
Clinical pregnancy rate (%) | 37.21 (16/43) | 6.06 (4/66) | < 0.001 |
Miscarriage rate (%) | 18.75 (3/16) | 75.00 (3/4) | 0.061 |
Live birth rate (%) | 30.23 (13/43) | 0 | < 0.001 |