Fig. 1From: Novel variants in TUBB8 gene cause multiple phenotypic abnormalities in human oocytes and early embryosPedigrees andTUBB8variants of 9 families. a Pedigrees and Sanger sequencing chromatograms of 9 families. The “〧” sign indicates infertility, the black circles represent affected individuals, the question marks indicate absence of DNA samples, ‘+’ means wild-type, and the red arrows indicate mutation loci. MT, mutant allele; WT, wild-type allele. b TA cloning of Family 7, the red arrows indicate mutation loci; WT, wild-type alleleBack to article page