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Table 2 Clinical characteristics of patients and their ART cycles

From: Novel variants in TUBB8 gene cause multiple phenotypic abnormalities in human oocytes and early embryos

Family no.

Age (years)

Duration of infertility (years)

Previous ART cycles

Total no. of oocytes retrieved

GV oocyte

MI oocyte

MII oocyte

Oocyte with abnormal morphology

Degen-

erated oocyte

Fertilized oocyte

Cleaved embryo

Usable embryo

Outcome of embryo transfer

Family 1

29

5

2

12

0

7

5

0

0

0

0

0

/

Family 2

34

7

3

15

1

0

14

0

0

8

7

2

Failure

Family 3

30

7

1

9

5

1

3

0

0

0

0

0

/

Family 4

35

8

1a

10

NA

NA

NA

NA

NA

NA

NA

0

/

   

1

2

2

0

0

0

0

0

0

0

/

Family 5

26

7

2

25

3

5

13

4

0

5

5

0

/

Family 6

31

6

1

6

0

0

6

0

0

3

2

0

/

Family 7

30

7

1

13

0

0

13

0

0

3

1

1

Failure

Family 8

35

5

2

10

0

1

2

6

1

0

0

0

/

Family 9

29

3

1

6

1

5

0

0

0

0

0

0

/

  1. ART, assisted reproductive technology; GV, germinal vesical; MI, metaphase I; MII, metaphase II; NA, not available
  2. a This ART cycle was conducted in other hospital