Effect of blastocyst shrinkage on assisted reproductive outcomes: a retrospective cohort study describing a new morphological evaluation of blastocyst pre-vitrification and post-warming

Table 2 Predictors of clinical pregnancy

Predictor	Odds ratio	95% CI	P value	Significance
Age	0.901	0.871–0.931	< 0.001	***
BMI	0.669	0.957–1.029	0.669
AMH	1.006	0.958–1.056	0.825
Basal FSH	0.975	0.928–1.025	0.328
Basal LH	1.048	0.982–1.118	0.161
Basal E2	1.000	0.993–1.006	0.882
Endometrial thickness	1.037	0.968–1.110	0.300
Serum E2 value on ET day	1.000	0.999–1.001	0.699
Serum P4 value on ET day	1.022	1.001–1.043	< 0.05	*
Non-GQB	0.388	0.268–0.561	< 0.001	***
Blastocyst stage reached after day 6	0.363	0.187–0.704	< 0.01	**
Blastocyst shrinkage post-warming and recovery culturing	0.389	0.245–0.618	< 0.001	***
Assisted hatching	0.762	0.510–1.139	0.185
Hyaluronic acid-enriched transfer medium	1.097	0.469–2.564	0.831

AMH anti-müllerian hormone, BMI body mass index, E2 estradiol, FSH follicle-stimulating hormone, GQB good-quality blastocyst, LH luteinising hormone, P4 progesterone, 95% CI 95% confidence interval, * p <0.05, ** p<0.01, *** p<0.001

ISSN: 1757-2215