Table 2 PGT-A cycle outcome of women in the GH and control groups after PSM
GH group N = 140 | Control group N = 272 | P-value | |
|---|---|---|---|
No. of OS cycles | 140 | 272 | 412 |
No. of OS cycles obtaining no blastocysts, n (%) | 32 (22.86) | 68 (25.00) | 0.63 |
No. of PGT-A cycles, n (%) | 108 (77.14) | 204 (75.00) | 0.63 |
No. of cycles obtaining euploid blastocysts n (%, per OS cycle) | 58 (41.43) | 74 (27.21) | 0.00 |
No. of embryos underwent PGT-A, n (%) | 231 | 492 | |
Euploid blastocysts | 75 (32.47) | 105 (21.34) | 0.001, 1.772 (1.249–2.514)a |
Aneuploid blastocysts | 147 (63.64) | 357 (72.56) | 0.015, 0.662 (0.474–0.924)a |
Mosaic blastocysts | 9 (3.90) | 30 (6.10) | 0.222, 0.624 (0.291–1.338) a |
No. of euploid blastocysts acquired | |||
Per OS cycle | 0.54 ± 0.74 | 0.39 ± 0.75 | 0.17 |
Per PGT-A cycle | 0.69 ± 0.78 | 0.51 ± 0.82 | 0.06 |
No. of aneuploid blastocysts acquired | |||
Per OS cycle | 1.06 ± 1.38 | 1.31 ± 1.50 | 0.04 |
Per PGT-A cycle | 1.36 ± 1.43 | 1.75 ± 1.45 | 0.03 |
Blastocyst euploid rate | |||
Per OS cycle | 0.27 ± 0.38 | 0.16 ± 0.30 | 0.00 |
Per PGT-A cycle | 0.35 ± 0.40 | 0.21 ± 0.33 | 0.00 |