Table 3 Subgroup analyses of PGT-A outcomes between the GH and control groups after PSM

Age 38–40 years (n = 180)

42/63 (66.67)

51/117 (43.59)

0.003

2.588 (1.367–4.902)

Age 41–43 years (n = 161)

12/49 (24.49)

19/112 (16.96)

0.265

1.587 (0.701–3.593)

Age 44–46 years (n = 71)

4/28 (14.29)

4/43 (9.3)

0.516

1.625 (0.371–7.112)

The euploid rate of blastocyst per embryo biopsied

Age 38–40 years (n = 400)

56/138 (40.58)

76/262 (29.01)

0.019

1.671 (1.085–2.575)

Age 41–43 years (n = 236)

15/64 (23.44)

25/172 (14.53)

0.105

1.800 (0.879–2.575)

Age 44–46 years (n = 87)

4/29 (13.79)

4/58 (6.90)

0.250

2.160 (0.499–9.345)

The aneuploid rate of blastocyst per embryo biopsied

Age 38–40 years (n = 400)

73/138 (52.90)

157/262 (59.92)

0.177

0.751 (0.496–1.138)

Age 41–43 years (n = 236)

49/64 (76.56)

145/172 (84.30)

0.167

0.608 (0.299–1.236)

Age 44–46 years (n = 87)

25/29 (86.21)

54/58 (93.10)

0.250

0.463 (0.107–2.003)

The mosaic rate of blastocyst per embryo biopsied

Age 38–40 years (n = 400)

9/138 (6.52)

29/262 (11.07)

0.140

0.561 (0.257–1.221)

Age 41–43 years (n = 236)

0/64 (0)

1/172 (0.58)

0.729

/

Age 44–46 years (n = 87)

0/29 (0)

0/58

/

/

Blastocyst euploid rate per OS cycle

Age 38–40 years (n = 180)

0.40 ± 0.37

0.24 ± 0.33

0.005

Age 41–43 years (n = 161)

0.19 ± 0.37

0.10 ± 0.27

0.085

Age 44–46 years

(n = 71)

0.13 ± 0.32

0.07 ± 0.23

0.406

Blastocyst euploid rate per biopsy cycle

Age 38–40 years (n = 146)

0.46 ± 0.37

0.31 ± 0.35

0.012

Age 41–43 years (n = 117)

0.26 ± 0.41

0.14 ± 0.30

0.081

Age 44–46 years (n = 49)

0.19 ± 0.39

0.10 ± 0.27

0.307