The potential influence of follicle diameter on natural cycle in vitro fertilization among women with diminished ovarian reserve: a retrospective cohort study

Table 2 The laboratory markers in different groups

	12-15 mm (N = 68)	16-17 mm (N = 171)	≥ 18 mm (N = 236)	H/χ²	P
E2/LH/P^†
E2 (pmol/L)	790.0 (593.0-965.0)	918.0 (683.0-1124.5)	921.0 (657.0-1263.0)	5.908	0.050
LH (mIU/mL)	13.25 (7.39–22.97)	10.9 (6.525–23.9)	8.72 (5.43–13.45)	16.158	0.000
P (nmol/L)	1.24 (0.81–1.88)	1.14 (0.85–1.745)	1.16 (0.8–1.73)	1.178	0.555
No. of canceled cycle^†	20/68 (27.9)	21/171 (12.3)^a	30/236 (12.7)^c	11.027	0.004
No. of oocytes retrieved^§	33/48 (64.7)	106/150 (70.7)	130/206 (67.8)	0.718	0.698
Insemination method
ICSI	9 (27.3)	17 (16.0)	27 (20.8)	2.189	0.335
IVF-ET	24 (72.7)	89 (84.0)	103 (79.2)
No. of 2PN fertilization^¶	21/33 (63.6)	80/106 (75.5)	78/130 (60.0) ^b	6.421	0.040
No. of embryo^¶	13/33 (33.3)	42/106 (37.5)	55/130 (38.9)	0.896	0.639
No. of good-quality embryo^¶	12/33 (36.4)	39/106 (36.8)	50/130 (38.5)	0.094	0.955
No. of fresh embryo transfers^&	9/13 (69.2)	29/42 (69.0)	35/55 (32.6)	0.662	0.832
No. of frozen embryo^&	4/13 (30.8)	13/42 (31.0)	20/55 (33.6)	0.662	0.832

Note: Continuous data are presented as median (IQR), while categorical variables were shown as numbers (percentages). The Chi-Square or Kruskal-Wallis tests were performed to examine the difference between the three groups. Multiple comparisons between every two groups were further performed. ^a represents there is a significant difference between group ≤ 15 mm and 16-17 mm; ^b represents there is a significant difference between group 16-17 mm and ≥ 18 mm and ^c represents a significant difference between group ≤ 15 mm and ≥ 18 mm
† denotes that the denominator was the total number of cycles in each group
§ indicates that the denominator excluded any canceled cycles
¶ signifies that the denominator was the number of cycles from which oocytes were obtained
& represents the denominator as the number of obtained embryos in each group

ISSN: 1757-2215