Fig. 1

The global transcriptome patterns of human oocytes and CCs at the different maturation stages. A Schematic illustration of the study workflow. germinal vesicle (GV, oocyte maturation arrested in the prophase of meiosis), metaphase I (MI, first meiotic metaphase), and metaphase II (MII, second meiotic metaphase). B Principal component analysis (PCA) of all samples shows significant separation between oocytes and CCs along PC1 by oocyte maturity but no apparent clustering within the CCs group showed by PC2. C Expression patterns of oocyte marker genes and D CCs maker genes in all samples; The CCs are shown in red, and the oocyte is shown in blue